Pharmaceutical Manufacturing
Protect Every Batch. Predict Every Risk. Boost Every Line.
Pharmaceutical manufacturing demands consistency, control, and compliance. The smallest vibration change can ruin a batch, trigger a deviation, or shut down production for days.
Why Pharmaceutical Manufacturing Chooses Chladni
A modern predictive system built for regulated, high-stakes manufacturing.
Zero integration risk. The sensor is wireless, non-invasive, and doesn't touch validated systems.
Instant insight. Your team sees drift, anomalies, and fault patterns early — with clear explanations.
Compliance-ready. Every event, reading, and fix is automatically documented.
Better decisions. AI + physics-based rules tell you the root cause and show the best next step.
What Goes Wrong Today (And Why It Matters)
In pharma, mechanical issues don't just stop machines — they destroy product.
A pump running slightly off normal flow
We use your vibration data to detect:
blend uniformity shifts
Micro-instability
A granulator with rising vibration
We use your vibration data to detect:
inconsistent particle size
Micro-instability
A misaligned drive
We use your vibration data to detect:
batch segregation or weight variability
Micro-instability
A worn bearing
We use your vibration data to detect:
contamination risk from friction particulates
Micro-instability
A fan motor drifting
We use your vibration data to detect:
airflow instability in critical rooms
Micro-instability
A TABLET PRESS TURRET VIBRATING
We use your vibration data to detect:
inconsistent tablet weight & hardness
Micro-instability
Explore the benefits of using Chladni
A modern predictive system built for regulated, high-stakes manufacturing.
| Scenario | Before | With Chladni |
|---|---|---|
| Production Stoppages | Unpredictable stoppages | A system that warns you weeks in advance |
| Batch Risk Detection | Batch risk detected during QC | Issues caught during production — and fixed early |
| Maintenance Visibility | Maintenance working blind | Your team sees which machine needs attention and why |
| Process Variability | Variability explained after the fact | Variability prevented before it touches product |
| Energy Efficiency | Energy-intensive equipment | Equipment running at optimal mechanical efficiency |
Real Impact for Pharma Manufacturers
These are examples of what facilities typically achieve with Chladni:
Fewer deviations and CAPAs thanks to early mechanical stability
Fewer deviations and CAPAs thanks to early mechanical stability
Fewer deviations and CAPAs thanks to early mechanical stability
Higher yield through reduced scrap and more consistent batches
Higher yield through reduced scrap and more consistent batches
Higher yield through reduced scrap and more consistent batches
Better decisions. AI + physics-based rules tell you the root cause and show the best next step.
Uneven product quality & rejected batches
Uneven product quality & rejected batches
Compliance-ready. Every event, reading, and fix is automatically documented.
Rising energy costs
Rising energy costs
How Chladni Works
Sense
Our sensor listens to every vibration pattern and builds the machine's personal health fingerprint.
Detect
AI spots early drift or abnormal behavior the moment it starts. Physics-based rules confirm what mechanical issue it resembles.
Predict
The system estimates how serious the issue is and how fast it's worsening.
Guide
The platform tells your team what's happening and what action will prevent it.
Document Automatically
Everything is logged and ready for audits and quality reviews.
What Teams Say
"Being able to prevent a deviation before it starts is a game-changer."
"Chladni shows us the real reason behind variability — before QC ever sees it."
"We save so much energy and scrap because problems never reach the product."
"Our machines finally behave the way they're supposed to."
"Being able to prevent a deviation before it starts is a game-changer."
"Chladni shows us the real reason behind variability — before QC ever sees it."
"We save so much energy and scrap because problems never reach the product."
"Our machines finally behave the way they're supposed to."
"Being able to prevent a deviation before it starts is a game-changer."
"Chladni shows us the real reason behind variability — before QC ever sees it."
"We save so much energy and scrap because problems never reach the product."
"Our machines finally behave the way they're supposed to."
"Being able to prevent a deviation before it starts is a game-changer."
"Chladni shows us the real reason behind variability — before QC ever sees it."
"We save so much energy and scrap because problems never reach the product."
"Our machines finally behave the way they're supposed to."
"Being able to prevent a deviation before it starts is a game-changer."
"Chladni shows us the real reason behind variability — before QC ever sees it."
"We save so much energy and scrap because problems never reach the product."
"Our machines finally behave the way they're supposed to."
"Being able to prevent a deviation before it starts is a game-changer."
"Chladni shows us the real reason behind variability — before QC ever sees it."
"We save so much energy and scrap because problems never reach the product."
"Our machines finally behave the way they're supposed to."
"Being able to prevent a deviation before it starts is a game-changer."
"Chladni shows us the real reason behind variability — before QC ever sees it."
"We save so much energy and scrap because problems never reach the product."
"Our machines finally behave the way they're supposed to."
"Being able to prevent a deviation before it starts is a game-changer."
"Chladni shows us the real reason behind variability — before QC ever sees it."
"We save so much energy and scrap because problems never reach the product."
"Our machines finally behave the way they're supposed to."
"Being able to prevent a deviation before it starts is a game-changer."
"Chladni shows us the real reason behind variability — before QC ever sees it."
"We save so much energy and scrap because problems never reach the product."
"Our machines finally behave the way they're supposed to."
"Being able to prevent a deviation before it starts is a game-changer."
"Chladni shows us the real reason behind variability — before QC ever sees it."
"We save so much energy and scrap because problems never reach the product."
"Our machines finally behave the way they're supposed to."
"Being able to prevent a deviation before it starts is a game-changer."
"Chladni shows us the real reason behind variability — before QC ever sees it."
"We save so much energy and scrap because problems never reach the product."
"Our machines finally behave the way they're supposed to."
"Being able to prevent a deviation before it starts is a game-changer."
"Chladni shows us the real reason behind variability — before QC ever sees it."
"We save so much energy and scrap because problems never reach the product."
"Our machines finally behave the way they're supposed to."
"Being able to prevent a deviation before it starts is a game-changer."
"Chladni shows us the real reason behind variability — before QC ever sees it."
"We save so much energy and scrap because problems never reach the product."
"Our machines finally behave the way they're supposed to."
"Being able to prevent a deviation before it starts is a game-changer."
"Chladni shows us the real reason behind variability — before QC ever sees it."
"We save so much energy and scrap because problems never reach the product."
"Our machines finally behave the way they're supposed to."
"Being able to prevent a deviation before it starts is a game-changer."
"Chladni shows us the real reason behind variability — before QC ever sees it."
"We save so much energy and scrap because problems never reach the product."
"Our machines finally behave the way they're supposed to."
"Being able to prevent a deviation before it starts is a game-changer."
"Chladni shows us the real reason behind variability — before QC ever sees it."
"We save so much energy and scrap because problems never reach the product."
"Our machines finally behave the way they're supposed to."
Chladni helps pharmaceutical facilities:
Avoid Batch Failures
Lower Energy Usage
Improve Equipment Performance
Protect Throughput
Reduce Deviations
Stay Compliant
Avoid Batch Failures
Lower Energy Usage
Improve Equipment Performance
Protect Throughput
Reduce Deviations
Stay Compliant
Avoid Batch Failures
Lower Energy Usage
Improve Equipment Performance
When machines behave perfectly, everything else follows.
Protect Throughput
Reduce Deviations
Stay Compliant
Avoid Batch Failures
Lower Energy Usage
Improve Equipment Performance
Frequently Asked
Questions
Will installing Chladni require us to re-validate our equipment or file a new regulatory submission?
No.Chladni is designed as a Non-Invasive Overlay.
No PLC Contact: Our sensors are completely independent of your machine’s control logic. We do not write back to the PLC or alter process parameters.
No Re-Validation: Because the installation does not impact the validated state or control strategy of the equipment, it typically qualifies as a "monitoring-only" addition, requiring no re-validation or complex change control.
How is the hardware installed? Do we need to shut down the line? A: Installation is wireless, tool-free, and requires zero downtime.
Installation is wireless, tool-free, and requires zero downtime.
Wireless & Non-Invasive: Our sensors attach to the external chassis of your assets (motors, pumps, gearboxes) using industrial-grade adhesive.
Rapid Deployment: A single line can be outfitted in under a few hours without stopping production.
Are the sensors safe for Cleanroom and GMP environments?
Yes. Our pharma-grade sensor nodes are designed with smooth, non-shedding enclosures that are IP67/IP69K rated. They are resistant to standard cleaning agents (VHP, Isopropyl Alcohol) and do not introduce particulate risk into sterile environments.
Does this system comply with Data Integrity (ALCOA+)?
Absolutely. While Chladni operates as a monitoring layer, all data is encrypted end-to-end, time-stamped, and immutable. We provide full audit trails for every alert and user interaction, supporting your site’s 21 CFR Part 11 and Annex 11 compliance strategies.
Can we integrate this data into our existing e-Logbook or MES?
Yes. We don't want to create a data silo. Chladni offers an open API to feed machine health status directly into your existing MES (e.g., Werum PAS-X, Rockwell PharmaSuite) or Quality Management System, automating the "Maintenance Required" entry in your electronic logbooks.
Will installing Chladni require us to re-validate our equipment or file a new regulatory submission?
No.Chladni is designed as a Non-Invasive Overlay.
No PLC Contact: Our sensors are completely independent of your machine’s control logic. We do not write back to the PLC or alter process parameters.
No Re-Validation: Because the installation does not impact the validated state or control strategy of the equipment, it typically qualifies as a "monitoring-only" addition, requiring no re-validation or complex change control.
How is the hardware installed? Do we need to shut down the line? A: Installation is wireless, tool-free, and requires zero downtime.
Installation is wireless, tool-free, and requires zero downtime.
Wireless & Non-Invasive: Our sensors attach to the external chassis of your assets (motors, pumps, gearboxes) using industrial-grade adhesive.
Rapid Deployment: A single line can be outfitted in under a few hours without stopping production.
Are the sensors safe for Cleanroom and GMP environments?
Yes. Our pharma-grade sensor nodes are designed with smooth, non-shedding enclosures that are IP67/IP69K rated. They are resistant to standard cleaning agents (VHP, Isopropyl Alcohol) and do not introduce particulate risk into sterile environments.
Does this system comply with Data Integrity (ALCOA+)?
Absolutely. While Chladni operates as a monitoring layer, all data is encrypted end-to-end, time-stamped, and immutable. We provide full audit trails for every alert and user interaction, supporting your site’s 21 CFR Part 11 and Annex 11 compliance strategies.
Can we integrate this data into our existing e-Logbook or MES?
Yes. We don't want to create a data silo. Chladni offers an open API to feed machine health status directly into your existing MES (e.g., Werum PAS-X, Rockwell PharmaSuite) or Quality Management System, automating the "Maintenance Required" entry in your electronic logbooks.
Will installing Chladni require us to re-validate our equipment or file a new regulatory submission?
No.Chladni is designed as a Non-Invasive Overlay.
No PLC Contact: Our sensors are completely independent of your machine’s control logic. We do not write back to the PLC or alter process parameters.
No Re-Validation: Because the installation does not impact the validated state or control strategy of the equipment, it typically qualifies as a "monitoring-only" addition, requiring no re-validation or complex change control.
How is the hardware installed? Do we need to shut down the line? A: Installation is wireless, tool-free, and requires zero downtime.
Installation is wireless, tool-free, and requires zero downtime.
Wireless & Non-Invasive: Our sensors attach to the external chassis of your assets (motors, pumps, gearboxes) using industrial-grade adhesive.
Rapid Deployment: A single line can be outfitted in under a few hours without stopping production.
Are the sensors safe for Cleanroom and GMP environments?
Yes. Our pharma-grade sensor nodes are designed with smooth, non-shedding enclosures that are IP67/IP69K rated. They are resistant to standard cleaning agents (VHP, Isopropyl Alcohol) and do not introduce particulate risk into sterile environments.
Does this system comply with Data Integrity (ALCOA+)?
Absolutely. While Chladni operates as a monitoring layer, all data is encrypted end-to-end, time-stamped, and immutable. We provide full audit trails for every alert and user interaction, supporting your site’s 21 CFR Part 11 and Annex 11 compliance strategies.
Can we integrate this data into our existing e-Logbook or MES?
Yes. We don't want to create a data silo. Chladni offers an open API to feed machine health status directly into your existing MES (e.g., Werum PAS-X, Rockwell PharmaSuite) or Quality Management System, automating the "Maintenance Required" entry in your electronic logbooks.
Will installing Chladni require us to re-validate our equipment or file a new regulatory submission?
No.Chladni is designed as a Non-Invasive Overlay.
No PLC Contact: Our sensors are completely independent of your machine’s control logic. We do not write back to the PLC or alter process parameters.
No Re-Validation: Because the installation does not impact the validated state or control strategy of the equipment, it typically qualifies as a "monitoring-only" addition, requiring no re-validation or complex change control.
How is the hardware installed? Do we need to shut down the line? A: Installation is wireless, tool-free, and requires zero downtime.
Installation is wireless, tool-free, and requires zero downtime.
Wireless & Non-Invasive: Our sensors attach to the external chassis of your assets (motors, pumps, gearboxes) using industrial-grade adhesive.
Rapid Deployment: A single line can be outfitted in under a few hours without stopping production.
Are the sensors safe for Cleanroom and GMP environments?
Yes. Our pharma-grade sensor nodes are designed with smooth, non-shedding enclosures that are IP67/IP69K rated. They are resistant to standard cleaning agents (VHP, Isopropyl Alcohol) and do not introduce particulate risk into sterile environments.
Does this system comply with Data Integrity (ALCOA+)?
Absolutely. While Chladni operates as a monitoring layer, all data is encrypted end-to-end, time-stamped, and immutable. We provide full audit trails for every alert and user interaction, supporting your site’s 21 CFR Part 11 and Annex 11 compliance strategies.
Can we integrate this data into our existing e-Logbook or MES?
Yes. We don't want to create a data silo. Chladni offers an open API to feed machine health status directly into your existing MES (e.g., Werum PAS-X, Rockwell PharmaSuite) or Quality Management System, automating the "Maintenance Required" entry in your electronic logbooks.