Technology

Industries

Contact

Blog

Book a demo

Technology

Industries

Contact

Blog

Book a demo

Technology

Industries

Contact

Blog

Get a quote

Pharmaceutical Manufacturing

Protect Every Batch. Predict Every Risk. Boost Every Line.

Pharmaceutical manufacturing demands consistency, control, and compliance. The smallest vibration change can ruin a batch, trigger a deviation, or shut down production for days.

Why Pharmaceutical Manufacturing Chooses Chladni

A modern predictive system built for regulated, high-stakes manufacturing.

Zero integration risk. The sensor is wireless, non-invasive, and doesn't touch validated systems.

Instant insight. Your team sees drift, anomalies, and fault patterns early — with clear explanations.

Compliance-ready. Every event, reading, and fix is automatically documented.

Better decisions. AI + physics-based rules tell you the root cause and show the best next step.

What Goes Wrong Today (And Why It Matters)

In pharma, mechanical issues don't just stop machines — they destroy product.

A pump running slightly off normal flow

We use your vibration data to detect:

blend uniformity shifts

Micro-instability

A granulator with rising vibration

We use your vibration data to detect:

inconsistent particle size

Micro-instability

A misaligned drive

We use your vibration data to detect:

batch segregation or weight variability

Micro-instability

A worn bearing

We use your vibration data to detect:

contamination risk from friction particulates

Micro-instability

A fan motor drifting

We use your vibration data to detect:

airflow instability in critical rooms

Micro-instability

A TABLET PRESS TURRET VIBRATING

We use your vibration data to detect:

inconsistent tablet weight & hardness

Micro-instability

Explore the benefits of using Chladni

A modern predictive system built for regulated, high-stakes manufacturing.

ScenarioBeforeWith Chladni
Production StoppagesUnpredictable stoppagesA system that warns you weeks in advance
Batch Risk DetectionBatch risk detected during QCIssues caught during production — and fixed early
Maintenance VisibilityMaintenance working blindYour team sees which machine needs attention and why
Process VariabilityVariability explained after the factVariability prevented before it touches product
Energy EfficiencyEnergy-intensive equipmentEquipment running at optimal mechanical efficiency
Scenario:Production Stoppages
Before
Unpredictable stoppages
With Chladni
A system that warns you weeks in advance
Scenario:Batch Risk Detection
Before
Batch risk detected during QC
With Chladni
Issues caught during production — and fixed early
Scenario:Maintenance Visibility
Before
Maintenance working blind
With Chladni
Your team sees which machine needs attention and why
Scenario:Process Variability
Before
Variability explained after the fact
With Chladni
Variability prevented before it touches product
Scenario:Energy Efficiency
Before
Energy-intensive equipment
With Chladni
Equipment running at optimal mechanical efficiency

Real Impact for Pharma Manufacturers

These are examples of what facilities typically achieve with Chladni:

Fewer deviations and CAPAs thanks to early mechanical stability

Higher yield through reduced scrap and more consistent batches

Better decisions. AI + physics-based rules tell you the root cause and show the best next step.

Uneven product quality & rejected batches

Compliance-ready. Every event, reading, and fix is automatically documented.

Rising energy costs

How Chladni Works

Sense

Our sensor listens to every vibration pattern and builds the machine's personal health fingerprint.

Detect

AI spots early drift or abnormal behavior the moment it starts. Physics-based rules confirm what mechanical issue it resembles.

Predict

The system estimates how serious the issue is and how fast it's worsening.

Guide

The platform tells your team what's happening and what action will prevent it.

Document Automatically

Everything is logged and ready for audits and quality reviews.

What Teams Say

Chladni helps pharmaceutical facilities:

  • Avoid Batch Failures

    Lower Energy Usage

    Improve Equipment Performance

  • Protect Throughput

  • Reduce Deviations

  • Stay Compliant

  • Avoid Batch Failures

  • Lower Energy Usage

  • Improve Equipment Performance

  • Protect Throughput

  • Reduce Deviations

  • Stay Compliant

  • Avoid Batch Failures

  • Lower Energy Usage

  • Improve Equipment Performance

When machines behave perfectly, everything else follows.

  • Protect Throughput

  • Reduce Deviations

  • Stay Compliant

  • Avoid Batch Failures

  • Lower Energy Usage

  • Improve Equipment Performance

Frequently Asked
Questions

Will installing Chladni require us to re-validate our equipment or file a new regulatory submission?

No.Chladni is designed as a Non-Invasive Overlay.

  • No PLC Contact: Our sensors are completely independent of your machine’s control logic. We do not write back to the PLC or alter process parameters.

  • No Re-Validation: Because the installation does not impact the validated state or control strategy of the equipment, it typically qualifies as a "monitoring-only" addition, requiring no re-validation or complex change control.

How is the hardware installed? Do we need to shut down the line? A: Installation is wireless, tool-free, and requires zero downtime.

Installation is wireless, tool-free, and requires zero downtime.

  • Wireless & Non-Invasive: Our sensors attach to the external chassis of your assets (motors, pumps, gearboxes) using industrial-grade adhesive.

  • Rapid Deployment: A single line can be outfitted in under a few hours without stopping production.

Are the sensors safe for Cleanroom and GMP environments?

Yes. Our pharma-grade sensor nodes are designed with smooth, non-shedding enclosures that are IP67/IP69K rated. They are resistant to standard cleaning agents (VHP, Isopropyl Alcohol) and do not introduce particulate risk into sterile environments.

Does this system comply with Data Integrity (ALCOA+)?

Absolutely. While Chladni operates as a monitoring layer, all data is encrypted end-to-end, time-stamped, and immutable. We provide full audit trails for every alert and user interaction, supporting your site’s 21 CFR Part 11 and Annex 11 compliance strategies.

Can we integrate this data into our existing e-Logbook or MES?

Yes. We don't want to create a data silo. Chladni offers an open API to feed machine health status directly into your existing MES (e.g., Werum PAS-X, Rockwell PharmaSuite) or Quality Management System, automating the "Maintenance Required" entry in your electronic logbooks.

Will installing Chladni require us to re-validate our equipment or file a new regulatory submission?

No.Chladni is designed as a Non-Invasive Overlay.

  • No PLC Contact: Our sensors are completely independent of your machine’s control logic. We do not write back to the PLC or alter process parameters.

  • No Re-Validation: Because the installation does not impact the validated state or control strategy of the equipment, it typically qualifies as a "monitoring-only" addition, requiring no re-validation or complex change control.

How is the hardware installed? Do we need to shut down the line? A: Installation is wireless, tool-free, and requires zero downtime.

Installation is wireless, tool-free, and requires zero downtime.

  • Wireless & Non-Invasive: Our sensors attach to the external chassis of your assets (motors, pumps, gearboxes) using industrial-grade adhesive.

  • Rapid Deployment: A single line can be outfitted in under a few hours without stopping production.

Are the sensors safe for Cleanroom and GMP environments?

Yes. Our pharma-grade sensor nodes are designed with smooth, non-shedding enclosures that are IP67/IP69K rated. They are resistant to standard cleaning agents (VHP, Isopropyl Alcohol) and do not introduce particulate risk into sterile environments.

Does this system comply with Data Integrity (ALCOA+)?

Absolutely. While Chladni operates as a monitoring layer, all data is encrypted end-to-end, time-stamped, and immutable. We provide full audit trails for every alert and user interaction, supporting your site’s 21 CFR Part 11 and Annex 11 compliance strategies.

Can we integrate this data into our existing e-Logbook or MES?

Yes. We don't want to create a data silo. Chladni offers an open API to feed machine health status directly into your existing MES (e.g., Werum PAS-X, Rockwell PharmaSuite) or Quality Management System, automating the "Maintenance Required" entry in your electronic logbooks.

Will installing Chladni require us to re-validate our equipment or file a new regulatory submission?

No.Chladni is designed as a Non-Invasive Overlay.

  • No PLC Contact: Our sensors are completely independent of your machine’s control logic. We do not write back to the PLC or alter process parameters.

  • No Re-Validation: Because the installation does not impact the validated state or control strategy of the equipment, it typically qualifies as a "monitoring-only" addition, requiring no re-validation or complex change control.

How is the hardware installed? Do we need to shut down the line? A: Installation is wireless, tool-free, and requires zero downtime.

Installation is wireless, tool-free, and requires zero downtime.

  • Wireless & Non-Invasive: Our sensors attach to the external chassis of your assets (motors, pumps, gearboxes) using industrial-grade adhesive.

  • Rapid Deployment: A single line can be outfitted in under a few hours without stopping production.

Are the sensors safe for Cleanroom and GMP environments?

Yes. Our pharma-grade sensor nodes are designed with smooth, non-shedding enclosures that are IP67/IP69K rated. They are resistant to standard cleaning agents (VHP, Isopropyl Alcohol) and do not introduce particulate risk into sterile environments.

Does this system comply with Data Integrity (ALCOA+)?

Absolutely. While Chladni operates as a monitoring layer, all data is encrypted end-to-end, time-stamped, and immutable. We provide full audit trails for every alert and user interaction, supporting your site’s 21 CFR Part 11 and Annex 11 compliance strategies.

Can we integrate this data into our existing e-Logbook or MES?

Yes. We don't want to create a data silo. Chladni offers an open API to feed machine health status directly into your existing MES (e.g., Werum PAS-X, Rockwell PharmaSuite) or Quality Management System, automating the "Maintenance Required" entry in your electronic logbooks.